Scientific Publications

ASCO 2020 Annual Gastrointestinal Cancers Symposium

SBP-101, a Polyamine Metabolic Inhibitor, Administered in Combination with Gemcitabine and Nab-paclitaxel, Shows Signals of Efficacy as First-Line Treatment for Subjects with Metastatic Pancreatic Ductal Adenocarcinoma

D. Kotasek, A. Nagrial, S. Lumba, N.C. Tebbutt, T. George, A.F. Hezel, D. Sigal, S.L. Smith, S. Gagnon, M.T. Cullen, M.J.Walker

poster preview

American Pancreatic Association Meeting

Effects of SBP-101 in a Mouse Model of Cerulein-induced Acute Pancreatitis

Michael J. Walker, Aurelia Lugea, Suzanne Gagnon, Thomas Neenan, Ajit K. Shah, Michael T. Cullen, Stephen Pandol – Sun BioPharma Inc. & Cedars-Sinai Medical Center

Sun BioPharma APA 2018 poster presentation

PancreasFest 2018

A Phase 1 Safety Study of SBP-101, a Polyamine Metabolic Inhibitor, for Pancreatic Ductal Adenocarcinoma

Niall C. Tebbutt, Dusan Kotasek, Mitesh J. Borad, Erkut Hasan Borazanci, Sheri Lynn Smith, Ajit K. Shah, Michael J. Walker, Michael T. Cullen, Suzanne Gagnon

A phase 1 safety study of SBP-101, a polyamine metabolic inhibitor, for pancreatic ductal adenocarcinoma (PDA).

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Digestive Disease Week 2017

SBP-101 Produces Exocrine Pancreatic Atrophy and Insufficiency While Preserving Islet Cell Function in Dogs

Michael J Walker MD, Suzanne Gagnon MD, Anthony Kiorpes DVM, PhD, Michael Cullen MD, Janet Wiegand BS, Raymond Bergeron PhD

SBP-101 Induces Apoptosis in Mouse Pancreatic Acinar Cells and Inhibits Polyamine-induced Proliferation

A. Sareen, A. Saluja, A. Shah, R. Dawra

American Pancreatic Association 2015

Evaluation of Human Pancreatic Cancer Cell Viability Following Administration of SBP-101 in the Presence and Absence of Gemcitabine and Nab-Paclitaxel

C. Baker, S. Arora, S. Gagnon, M. Cullen, A. Shah

PancreasFest 2015

Efficacy of SBP-101 Against Human Pancreatic Ductal Adenocarcinoma Following Orthotopic Implantation of L3.6pl Pancreatic Cancer Cells into Nude Mice

Ajit K. Shah, Michael T. Cullen, Cheryl H. Baker

AACR 2014 abstract #3128

Efficacy of Diethyldihydroxyhomospermine Against Human Pancreatic Adenocarcinoma Using Orthotopic Implantation of Human Pancreatic L3.6pl Cells into the Pancreas of Nude Mice

Shah AK, Cullen MT, Baker CH.

Poster Abstract